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Researchers Identify Sustainable Source of Immunodeficiency Virus-resistant Immune Cells
Genetic engineering can make immune cells resistant to infection with human or monkey (simian) immunodeficiency virus (HIV and SIV, respectively). Recently, treatment with HIV-resistant immune cells has given encouraging results in patients. Stem cell researchers have now found ways of making large numbers of virus-resistant immune cells from monkeys, allowing future studies on safety and efficacy of immune therapy in a pre-clinical animal model. This encouraging research, recently published in Stem Cell Reports, will help scientists consider alternative approaches to treating HIV, the virus causing AIDS.
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